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Search resuls for: "United Therapeutics Corporation"


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A severely ill 54-year-old woman earlier this month became the second person to receive a kidney transplanted from a genetically modified pig, surgeons at NYU Langone Health in New York announced on Wednesday. The patient, who had both heart failure and kidney failure, was given the organ on April 12, just eight days after receiving a mechanical heart pump. Surgical teams at NYU Langone carried out the two procedures over the course of nine days. The kidney came from a genetically engineered pig provided by United Therapeutics Corporation, a biotech company. The pig carried a gene for producing a sugar called alpha-gal that had been “knocked out,” or blocked.
Persons: NYU Langone, Lisa Pisano, Organizations: NYU Langone Health, NYU, United Therapeutics Corporation Locations: New York, New Jersey
A number of studies last year demonstrated that pig kidneys that had been transplanted into brain-dead individuals made urine, an essential function, for short periods of time. “The really new finding here is that these pig kidneys can clear enough creatinine to support an adult human,” Dr. Locke said. “If you want to have life-sustaining kidney function, the kidneys have to do more than just make urine,” Dr. Locke said. A few months later, researchers at the University of Maryland transplanted a heart from a genetically modified pig into a 57-year-old patient with heart failure. So far, transplants of genetically modified pig kidneys have been made only to brain-dead patients.
Persons: , Jayme Locke, Dr, Locke Organizations: Transplant Institute, NYU Langone Health, University of Maryland, Revivicor, United Therapeutics Corporation, Langone Health, Food and Drug Administration Locations: Alabama, New York
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